Silencing the <i>hsp25</i> Gene Eliminates Migration Capability of the Highly Metastatic Murine 4T1 Breast Adenocarcinoma Cell
نویسندگان
چکیده
منابع مشابه
Silencing the hsp25 gene eliminates migration capability of the highly metastatic murine 4T1 breast adenocarcinoma cell.
The 25-kDa heat shock protein (Hsp25) is associated with various malignancies and is expressed at high levels in biopsies as well as circulating in the serum of breast cancer patients. In this study, we used RNA interference technology to silence the hsp25 gene in 4T1 breast adenocarcinoma cells, known as a poorly immunogenic, highly metastatic cell line. We demonstrate that transfection of 4T1...
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ژورنال
عنوان ژورنال: Tumor Biology
سال: 2006
ISSN: 1423-0380,1010-4283
DOI: 10.1159/000090152